PEDF antibody (10R-1032)

Mouse monoclonal PEDF antibody

Synonyms Monoclonal PEDF antibody, Anti-PEDF antibody, Proliferation inducing protein 35 antibody, EPC1 antibody, SERPIN F1 antibody, Pigment epithelium-derived factor antibody, SERPIN F1 antibody, Pigment epithelium-derived factor EP 1c antibody, Pigment epithelium-derived factor antibody, EP-1c antibody, SERPINF 1 antibody, PIG35 antibody, PIG35 antibody, Anti PEDF antibody , Proliferation inducing protein 35 antibody, EP-1c antibody, Pigment epithelium derived factor antibody, SERPINF1 antibody, PIG 35 antibody, EPC1 antibody, Pigment epithelium-derived factor EP 1c antibody, Serpin peptidase inhibitor clade F member 1 antibody, SERPINF 1 antibody, Serpin peptidase inhibitor clade F member 1 antibody, SERPINF1 antibody, PEDF antibody, PIG 35 antibody, Pigment epithelium derived factor antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen PEDF antibody was raised in mouse using recombinant human PEDF (19-418 aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 1C4
Isotype IgG1 kappa
Source Anti-human PEDF antibody, clone 1C4, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PEDF protein.
Method of Purification PEDF antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Pigment epithelium-derived factor (PEDF) is a 50kDa glycoprotein and member of the serpin superfamily without any activity of serine protease. PEDF is an angiogenesis inhibitor with neurotrophic properties, balances angiogenesis in the eye and blocks tumor progression. That is, in neuronal cell, PEDF is promoting cell survival and differentiation, however, when endothelial cells are exposed to PEDF, their cell migration and proliferation are inhibited, and they undergo apoptosis.

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Availability: In stock

Price: £212.33
Size: 100 ul
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