Peroxiredoxin 2 protein (30R-1268)

Purified recombinant Human Peroxiredoxin 2 protein

Synonyms Peroxiredoxin 2, Thiol specific antioxidant protein protein, Thiol Specific Antioxidant 1 protein, Peroxiredoxin -2 protein, NKEFB protein, Thioredoxin Dependent Peroxide Reductase 1 protein, Peroxiredoxin 2, Peroxiredoxin 2 protein, Thioredoxin Peroxidase 1 protein, Torin., Peroxiredoxin -2, Natural Killer Enhancing Factor B protein, MGC4104 protein, PRXII protein, PRDX2 protein, Natural killer cell enhancing factor B protein, TDPX1 protein, Peroxiredoxin 2 protein, TDPX1 protein, TSA protein, PRP protein, PRDX 2 protein, PRX2 protein, NKEF B protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Peroxiredoxin 2 protein (30R-1268)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-198 amino acids: MASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 21.8 kDa (198aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Usage & Assay Information

Bioactivity Activity Specific activity is >2,000 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute.

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Peroxiredoxin 2, also known as PRDX2, is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Peroxiredoxin 2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. If Peroxiredoxin 2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. Recombinant human Peroxiredoxin 2 protein was expressed in E. coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of Peroxiredoxin 2 protein (30R-1268) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £272.43
Size: 100 ug
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