Peroxiredoxin 3 protein (30R-1321)

Purified recombinant Human Peroxiredoxin 3 protein

Synonyms MER5 protein, AOP1 protein, SP22 protein, Peroxiredoxin -3 protein, Peroxiredoxin 3, PRDX3 protein, PRX III protein, PRX3 protein, Peroxiredoxin 3 protein, Peroxiredoxin-3, mitochondrial Antioxidant Protein 1 protein, Antioxidant protein 1 (AOP-1) protein, Peroxiredoxin 3, Thioredoxin-dependent peroxide reductase protein, Peroxiredoxin 3 protein, Peroxiredoxin -3, Thioredoxin-dependent peroxide reductase mitochondrial protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Specifications

Residues 63-256 amino acids: MPAVTQHAPY FKGTAVVNGE FKDLSLDDFK GKYLVLFFYP LDFTFVCPTE IVAFSDKANE FHDVNCEVVA VSVDSHFSHL AWINTPRKNG GLGHMNIALL SDLTKQISRD YGVLLEGSGL ALRGLFIIDP NGVIKHLSVN DLPVGRSVEE TLRLVKAFQY VETHGEVCPA NWTPDSPTIK PSPAASKEYF QKVNQ
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 21.5 kDa (195aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Usage & Assay Information

Bioactivity Specific activity is >2,000 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for 1minute.

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Peroxiredoxin 3, also known as PRDX3, is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Peroxiredoxin 3 is specifically localized in mitochondria and believed to play important roles in the regulation of cellular redox status by serving as a primary line of defense against H2O2 produced during respiration. Recombinant human Peroxiredoxin 3 protein was expressed in E. coli and purified by using conventional chromatography techniques.

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Availability: In stock

Price: £272.43
Size: 100 ug
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