PFKM antibody (70R-10259)

Affinity purified rabbit polyclonal PFKM antibody

Synonyms Polyclonal PFKM antibody, Anti-PFKM antibody, muscle antibody, PFKX antibody, PFKA antibody, GSD7 antibody, MGC8699 antibody, PFK1 antibody, phosphofructokinase, PFK-1 antibody
Cross Reactivity Human
Applications WB
Immunogen PFKM antibody was raised in rabbit using the C terminal of PFKM as the immunogen
Assay Information PFKM Blocking Peptide, catalog no. 33R-7817, is also available for use as a blocking control in assays to test for specificity of this PFKM antibody

Images

Western Blot analysis using PFKM antibody (70R-10259)

Western Blot showing PFKM antibody used at a concentration of 1 ug/ml against Fetal Heart Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

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Images

  • Western Blot analysis using PFKM antibody (70R-10259) | Western Blot showing PFKM antibody used at a concentration of 1 ug/ml against Fetal Heart Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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