phospho-PDGFR beta antibody (20R-PR014)

Rabbit polyclonal phospho-PDGFR beta antibody (Tyr716)

Synonyms Polyclonal phospho-PDGFR beta antibody, Anti-phospho-PDGFR beta antibody, pPDGFRB antibody, phospho-PDGFR beta antibody, Phosphorylated Platelet Derived Growth Factor Receptor beta antibody, pPDGFR beta antibody, phos-PDGFR beta antibody, PDGFR beta (Tyr 716) antibody
Specificity Human PDGFR beta phosphorylated at Tyr716
Cross Reactivity Avian, chicken, mouse, rat
Applications WB
Immunogen Phospho-PDGFR receptor beta antibody was raised in rabbit using peptide corresponding to amino acids 710-718 of human PDGF receptor-beta (C-PPSAELPYSN) as the immunogen.

Images

Western Blot analysis using phospho-PDGFR beta antibody (20R-PR014)

Lysates from unstimulated (lane 1) and PDGF-BB-stimulated (lane 2) HFF cells were probed with phospho-PDGFR beta (20R-PR014) (4ug/ml)

Specifications

Host Rabbit
Isotype IgG
Method of Purification phospho-PDGFR Receptor beta antibody was purified by Protein A chromatography.
Molecular Weight 190 kDa (predicted detection band MW)
Form & Buffer 100mM Tris-glycine, pH 7.4, with 150mM NaCl, 0.05% NaN3 and 30% glycerol.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.

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Images

  • Western Blot analysis using phospho-PDGFR beta antibody (20R-PR014) | Lysates from unstimulated (lane 1) and PDGF-BB-stimulated (lane 2) HFF cells were probed with phospho-PDGFR beta (20R-PR014) (4ug/ml)
  • Western blot analysis using phospho-PDGFR beta antibody (20R-PR014) | Western blot analysis of Lysates from unstimulated (lane 1) and PDGF-BB-stimulated (lane 2) HFF cells probed with Anti-phospho-PDGF Receptor beta (Tyr716) ( 4ug/ml).

Availability: In stock

Price: £340.53
Size: 200 ug
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