Plakophilin 1 antibody (10R-P130a)

Mouse monoclonal Plakophilin 1 antibody

Synonyms Monoclonal Plakophilin 1 antibody, Anti-Plakophilin 1 antibody
Specificity Bovine plakophilin 1
Cross Reactivity Cow, frog, human, pig
Applications ELISA, IHC-F, IHC-P, WB
Immunogen Plakophilin 1 antibody was raised in mouse using plakophilin 1 ( “band 6 polypeptide” of Bovine Muzzle epidermis) as the immunogen.

Specifications

Host Mouse
Clone PP1-5C2
Isotype IgG1
Grade & Purity Culture supernatant
Form & Buffer Hybridoma culture supernatant with 0.09% NaN3

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.

General Information

Biological Significance Plakophilin-1 is a protein that in humans is encoded by the PKP1 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome.

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Availability: In stock

Price: £260.41
Size: 5 ml
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