Polymyxin B Sulfate (USP grade powder) (51R-U547007)
Polymyxin B Sulfate (USP grade powder) chemical reference substance
|Form & Buffer||Supplied as a powder.|
|Biological Significance||Polymyxins are antibiotics, with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. They are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria due to their specificity for the lipopolysaccharide molecule that exists within many Gram-negative outer membranes.|
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