PPP1R14A antibody (10R-1093)

Mouse monoclonal PPP1R14A antibody

Synonyms Monoclonal PPP1R14A antibody, Anti-PPP1R14A antibody, regulatory (inhibitor) subunit 14A CPI 17 antibody, CPI 17alpha antibody, PPPR4A 1, CPI17 antibody, PPPR4A-1 antibody, PPPR4A 1 antibody, PPP1R14A antibody, Protein phosphatase 1 antibody, PKC potentiated inhibitory protein of PP1 antibody, Protein phosphatase 1 regulatory subunit 14A antibody, regulatory (inhibitor) subunit 14A antibody, PPP1R14A, Regulatory subunit 14A antibody, Protein phosphatase 1 antibody, CPI 17 alpha antibody, CPI-17 antibody, CPI17 antibody, PPP1INL antibody, Protein phosphatase 1 regulatory (inhibitor) subunit 14A antibody, PPPR4A-1
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen PPP1R14A antibody was raised in mouse using recombinant human PPP1R14A (1-147aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 4H10
Isotype IgG2a kappa
Source Anti-human PPP1R14A antibody, clone 4H10, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPP1R14A protein.
Method of Purification PPP1R14A antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization.

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Availability: In stock

Price: £212.33
Size: 100 ul
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