Presenilin 1 antibody (20-PG71)

Goat polyclonal Presenilin 1 antibody

Synonyms Polyclonal Presenilin 1 antibody, Anti-Presenilin 1 antibody, Presenilin -1 antibody, PS-1 antibody, PS1 antibody, Presenilin 1 antibody, Presenilin 1, Presenilin -1, Presenilin-1 antibody, Presenilin 1
Specificity Human presenilin-1
Cross Reactivity To be determined by end-user
Applications ELISA, IHC, WB
Immunogen Presenilin 1 antibody was raised in goat using peptide (AQMSEDNHLSNTVRSQNDNR) as the immunogen.

Specifications

Host Goat
Form & Buffer Supplied as liquid neat serum without preservative.

Usage & Assay Information

Usage Recommendations ELISA: 1:5,000, IHC: 1:1,000, WB: 1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The presenilin-1 (PS-1) gene was found on chromosome 14 and is responsible for an early onset form of Alzheimer's disease (AD) that accounts for 70-80% of the inherited forms of Alzheimer's. It is a membrane protein that has a region where at least seven mutations have been identified in family members with AD. The gene sequence of PS-1 does not match any known human gene sequences with the exception of PS-2; but has been found to be a new class of aspartic?proteases. It has now been identified as one of the g-secretase proteases.

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Availability: In stock

Price: £348.14
Size: 100 ul
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