Proteinase 3 protein (30R-AP027)

Purified native Human Proteinase 3 protein

Synonyms Proteinase 3, PR-3 protein, PR3 protein, Proteinase 3, Proteinase 3 protein, Proteinase-3, Proteinase-3 protein
Species Human
Protein Type Native
Applications User optimized

Specifications

Source Purulent human sputum
Grade & Purity > 95% pure
Molecular Weight 29 kDa
Form & Buffer Liquid in 50mM NaOAc, pH 5.0, with 600mM NaCl.

Usage & Assay Information

Bioactivity 60-75 units/mg protein - One enzyme unit will hydrolyze 1uMole of Boc-Ala-Ala-Nva-SBzl per minute at pH 7.5 at 25 DEG C.

Storage & Safety

Storage 4°C shipping only. Upon receipt store at -20°C. Avoid repeat freeze-thaws.
Biohazard Information All of the human sputum leucocyte enzymes are prepared from human sputum shown to be non-reactive for HIV antibody, and negative for Hepatitis C antibody.

General Information

Biological Significance Proteinase 3 also known as PRTN3 is an enzyme which in humans is encoded by the PRTN3 gene. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides.

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Availability: In stock

Price: £476.74
Size: 100 ug
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