PTGES antibody (20R-PR093)

Rabbit polyclonal PTGES antibody

Synonyms Polyclonal PTGES antibody, Anti-PTGES antibody, prostaglandin e synthase antibody, mgst1l1 antibody, pig12 antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications IHC-P
Immunogen PTGES antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Specifications

Host Rabbit
Method of Purification PTGES antibody was purified by affinity chromatography.
Form & Buffer Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations IHC-P: 10 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53-induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

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Availability: In stock

Price: £334.12
Size: 50 ug
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