PUMA antibody (70R-PR054)

Affinity purified Rabbit polyclonal PUMA antibody

Synonyms Polyclonal PUMA antibody, Anti-PUMA antibody, p53 Upregulated Modulator of Apoptosis
Specificity Human
Cross Reactivity To be determined by end-user
Applications WB
Immunogen PUMA antibody was raised in rabbit using 17 residue sequence 29-55 [EQHLESPVPSAPGALAG] found in the exon-3-encoded region in the human PUMA-Alpha and PUMA-Beta forms of the protein as the immunogen.

Specifications

Host Rabbit
Isotype IgG
Method of Purification PUMA antibody was purified by affinity chromatography.
Form & Buffer Affinity purified IgG supplied in PBS with 0.02% NaN3.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance PUMA (p53 upregulated modulator of apoptosis) is a target for activation by the p53 tumor-suppressor gene. Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.

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Availability: In stock

Price: £200.31
Size: 100 ug
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