RAGE antibody (70R-1663)

Rabbit polyclonal AGER antibody raised against the C terminal of AGER

Synonyms Polyclonal RAGE antibody, Anti-RAGE antibody, MGC22357 antibody, Advanced Glycosylation End Product-Specific Receptor antibody, AGER antibody
Specificity RAGE antibody was raised against the C terminal of AGER
Cross Reactivity Human
Applications IHC, WB
Immunogen RAGE antibody was raised using the C terminal of AGER corresponding to a region with amino acids RIRAGNSSPGPGDPGRPGDSRPAHWGHLVAKAATPRRGEEGPRKPGGRGG
Assay Information RAGE Blocking Peptide, catalog no. 33R-7977, is also available for use as a blocking control in assays to test for specificity of this RAGE antibody

Images

Immunohistochemical staining using RAGE antibody (70R-1663)

RAGE antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X

Specifications

Host Rabbit
Method of Purification Total IgG Protein A purified
Molecular Weight 38 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of AGER antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 2.5 ug/ml; IHC: 4-8 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance AGER mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. It is receptor for amyloid beta peptide.

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Images

  • Immunohistochemical staining using RAGE antibody (70R-1663) | RAGE antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X
  • Western Blot analysis using RAGE antibody (70R-1663) | RAGE antibody (70R-1663) used at 2.5 ug/ml to detect target protein.

Availability: In stock

Price: £220.34
Size: 100 ug
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