RAN protein (His tag) (80R-1353)
Purified recombinant Human RAN protein
|Synonyms||, Ras like protein TC4 protein, GTPase Ran protein, LPS protein, Androgen receptor associated protein 24 protein, RASL2 8 protein, ARA24 protein, RAN member RAS oncogene family protein, Gsp1 protein, GTP binding nuclear protein RAN protein, member RAS oncogene family protein, RAN protein, TC4 protein, ARA 24 protein|
Coomassie Blue stained SDS-PAGE of RAN protein (His tag) (80R-1353)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-216 amino acids: MGSSHHHHHH SSGLVPRGSH MAAQGEPQVQ FKLVLVGDGG TGKTTFVKRH LTGEFEKKYV ATLGVEVHPL VFHTNRGPIK FNVWDTAGQE KFGGLRDGYY IQAQCAIIMF DVTSRVTYKN VPNWHRDLVR VCENIPIVLC GNKVDIKDRK VKAKSIVFHR KKNLQYYDIS AKSNYNFEKP FLWLARKLIG DPNLEFVAMP ALAPPEVVMD PALAAQYEHD LEVAQTTALP DEDDDL|
|Grade & Purity||> 90% pure|
|Molecular Weight||26.5 kDa (236aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||RAN, member RAS oncogene family, also known as RAN, is a small GTPase of the Ras superfamily that controls nucleocytoplasmic transport. It is involved in the directionality of the process that is regulated by GTP hydrolysis. Ran shuttles between the nucleus and the cytoplasm. Unlike many other regulatory GTPases, Ran is not posttranslationally modified so that it can be targeted to the subcellular compartment where it acts. Rather, RanGTP has been thought to be localized by the differential localization of Ran regulators. Recombinant human RAN, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques|
Sorry, but there are no references currently for this product.
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product