Relaxin 3 protein (30R-AR029)

Purified recombinant Human Relaxin 3 protein

Synonyms Relaxin-3 protein, Relaxin-3 protein, INSL7 protein, Relaxin-3, H3 relaxin protein, Insulin-like peptide-7 protein, Relaxin 3, Relaxin 3 protein, Relaxin 3
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of Relaxin 3 protein corresponding to amino acids (A-chain): DVLAGLSSS CCKWGCSKSE ISSLC and (B-chain): RAAPYGVRL CGREFIRAVI FTCGGSRW
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 5.5 kDa
Form & Buffer Supplied as a lyophilized powder.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance Relaxin-3 (H3 relaxin, Insulin-like peptide-7, INSL7) is a secreted protein structurally related to insulin, which is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as ?somatostatin-like? or ?angiotensin-like? peptide receptor, and also binds specifically to the LGR7 receptor, previously identified as an ?orphan? G protein coupled receptor. Signaling by Relaxin-3 through its target receptors is, most likely, part of a CNS processing system, activated in response to signaling by neuropeptides and other factors. Intracerebroventricular injections of Relaxin-3 have been shown to cause a significant increase of food intake and body weight in Wistar rats.

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Availability: In stock

Price: £180.28
Size: 25 ug
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