RGS21 protein (His tag) (80R-1918)
Purified recombinant RGS21 protein
|Synonyms||RGS21, RGS-21, RGS 21 protein, RGS-21 protein, RGS 21, Regulator of G-protein signaling 21 protein|
|Assay Information||RGS21 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.|
Coomassie Blue stained SDS-PAGE of RGS21 protein (His tag) (80R-1918)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-152 amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMPVKCC FYRSPTAETM TWSENMDTLL ANQAGLDAFR IFLKSEFSEE NVEFWLACED FKKTKNADKI ASKAKMIYSE FIEADAPKEI NIDFGTRDLI SKNIAEPTLK CFDEAQKLIY CLMAKDSFPR FLKSEIYKKL VNSQQVPNHK KWLPFL|
|Grade & Purity||> 90% pure|
|Molecular Weight||20.2 kDa|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, with 1mM DTT, 30% glycerol and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C or -70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Regulator of G-protein signaling 21, also known as RGS21, is a RGS family member and regulatory molecule that acts as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Recombinant human RGS21 human, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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