RGS5 protein (His tag) (80R-1931)

Purified recombinant RGS5 protein

Synonyms MSTP129 protein, RGS-5, Regulator of G-protein signaling 5 protein, RGS 5 protein, MSTP106 protein, MST129 protein, RGS5, RGS-5 protein, RGS 5, MST092 protein, MSTP032 protein, MSTP092 protein, MST106 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE
Assay Information RGS5 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Images

Coomassie Blue stained SDS-PAGE of RGS5 protein (His tag) (80R-1931)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-181 amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMCKGLA ALPHSCLERA KEIKIKLGIL LQKPDSVGDL VIPYNEKPEK PAKTQKTSLD EALQWRDSLD KLLQNNYGLA SFKSFLKSEF SEENLEFWIA CEDYKKIKSP AKMAEKAKQI YEEFIQTEAP KEVNIDHFTK DITMKNLVEP SLSSFDMAQK RIHALMEKDS LPRFVRSEFY QELIK
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 23.5 kDa
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, with 20% glycerol, 0.1M NaCl and 1mM DTT.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C or -70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance RGS5, also known as regulator of G-protein signaling 5, binds directly to activated G alpha subunits and acts as a GTPase-activating protein (GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both G alpha-GTP and G beta gamma. Vascular endothelial cells express the RGS protein RGS5, where it correlates with capillary morphogenesis, thus rendering it a candidate gene involved in capillary growth, angiogenesis, and also potentially the pathophysiology of stroke. Recombinant human RGS5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of RGS5 protein (His tag) (80R-1931) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £204.32
Size: 100 ug
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