RHO antibody (70R-9928)
Affinity purified rabbit polyclonal RHO antibody
|Synonyms||Polyclonal RHO antibody, Anti-RHO antibody, MGC138311 antibody, RP4 antibody, rhodopsin antibody, MGC138309 antibody, OPN2 antibody, CSNBAD1 antibody|
|Immunogen||RHO antibody was raised in rabbit using the C terminal of RHO as the immunogen|
|Assay Information||RHO Blocking Peptide, catalog no. 33R-7510, is also available for use as a blocking control in assays to test for specificity of this RHO antibody|
Western Blot analysis using RHO antibody (70R-9928)
RHO antibody (70R-9928) used at 0.2-1 ug/ml to detect target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.|
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