RQCD1 protein (His tag) (80R-1548)
Purified recombinant Human RQCD1 protein
|Synonyms||Cell differentiation protein RCD1 homolog protein, RQCD 1 protein, RQCD1, RCD1, CNOT9 protein, RQCD-1, RQCD-1 protein, RQCD 1, CT129 protein|
Coomassie Blue stained SDS-PAGE of RQCD1 protein (His tag) (80R-1548)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-299 amino acids: MGSSHHHHHH SSGLVPRGSH MHSLATAAPV PTTLAQVDRE KIYQWINELS SPETRENALL ELSKKRESVP DLAPMLWHSF GTIAALLQEI VNIYPSINPP TLTAHQSNRV CNALALLQCV ASHPETRSAF LAAHIPLFLY PFLHTVSKTR PFEYLRLTSL GVIGALVKTD EQEVINFLLT TEIIPLCLRI MESGSELSKT VATFILQKIL LDDTGLAYIC QTYERFSHVA MILGKMVLQL SKEPSARLLK HVVRCYLRLS DNPRAREALR QCLPDQLKDT TFAQVLKDDT TTKRWLAQLV KNLQEGQVTD PRGIPLPPQ|
|Grade & Purity||> 95% pure|
|Molecular Weight||35.7 kDa (319aa) confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0.1M NaCl, 1mM DTT and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||RQCD1, also known as RCD1, is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation. It down-regulates MYB- and JUN-dependent transcription and may play a role in cell differentiation. RQCD1 also plays a role in retinoic acid-controlled lung development. Recombinant human RQCD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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