SCF protein (30R-1145)
Purified recombinant Human SCF protein
|Synonyms||Clo protein, MMIF protein, Stem cell factor protein, Steel protein, contrasted protein, Mgf protein, Kitlg protein, Sl protein, glycosylation inhibiting factor (GIF) protein, Gb protein, Con protein, Kitl protein, GLIF protein, Stem cell factor, SCF protein, SLF protein, mouse SCF protein, SF protein|
Coomassie Blue stained SDS-PAGE of SCF protein (30R-1145)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||26-189 amino acids: MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA|
|Grade & Purity||> 95% pure|
|Molecular Weight||18 kDa (165 aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 50mM Tris, pH 8.0, containing 0.5mM DTT, and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration. Recombinant human MIF was expressed in E. coli and purified by conventional chromatography techniques.|
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