Serotonin Transporter antibody (10R-S108a)

Mouse monoclonal Serotonin Transporter antibody

Synonyms Monoclonal Serotonin Transporter antibody, Anti-Serotonin Transporter antibody, SERT antibody, SERT antibody, Anti Serotonin Transporter antibody, Serotonin Transporter antibody
Specificity Rat
Cross Reactivity To be determined by end-user
Applications IHC
Immunogen Serotonin transporter antibody was raised in mouse using at serotonin transporter, N-terminus/GST Fusion protein (amino acids 1-85) as the immunogen.

Images

Immunohistochemical staining using Serotonin Transporter antibody (10R-S108a)

Mouse anti-Serotonin Transporter antibody localization of serotonin transporter in rat brain. The antibody reacts with fibers in cerebral cortex (shown is cingulate cortex) and other brain regions innervated by serotonin fibers, as well as with cell bodies in the brainstem raphe (inset).

Specifications

Host Mouse
Clone MAB1564
Isotype IgG1
Method of Purification Serotonin Transporter antibody was purified by Protein A affinity chromatography.
Form & Buffer 0.02M PO4 buffer, pH 7.6, with 0.25M NaCl, and 0.1% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations IHC: 0.5-1 ug/ml

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Serotonin (5-hydroxytryptamine) is a catecholamine with a molecular weight of 176 Daltons that is formed in gastrointestinal enteroendocrine cells, platelets, brain and spinal cord. It is secreted by enterochromaffin cells (EC) in the stomach, intestines and appendix and is believed to play a role in gut motility. Serotonin is the major secretion of carcinoid tumors. It is metabolized with the production of 5-hydroxy-indoleacetic acid.

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Images

  • Immunohistochemical staining using Serotonin Transporter antibody (10R-S108a) | Mouse anti-Serotonin Transporter  antibody localization of serotonin transporter in rat brain. The antibody reacts with fibers in cerebral cortex (shown is cingulate cortex) and other brain regions innervated by serotonin fibers, as well as with cell bodies in the brainstem raphe (inset).

Availability: In stock

Price: £300.47
Size: 100 ug
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