Serpin A5 protein (His tag) (80R-1216)

Purified recombinant Human Serpin A5 protein

Synonyms Plasma serine protease inhibitor protein, Protein C inhibitor protein, PROCI protein, Serpin A5, PAI 3 protein, Serpin A-5 protein, Plasminogen activator inhibitor 3 protein, PLANH3 protein, Serpin A-5, Plasminogen activator inhibitor III protein, Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 5 protein, Serpin A5 protein, Serpin peptidase inhibitor clade A member 5 protein, Serpin A 5, member 5 Acrosomal serine protease inhibitor protein, clade A protein, Serpin A 5 protein, SerpinA5., IPSP protein, PLANH 3 protein, Serpin peptidase inhibitor protein, PCI protein, PAI3 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Serpin A5 protein (His tag) (80R-1216)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 20-406 amino acids: MGSSHHHHHH SSGLVPRGSH MHRHHPREMK KRVEDLHVGA TVAPSSRRDF TFDLYRALAS AAPSQNIFFS PVSISMSLAM LSLGAGSSTK MQILEGLGLN LQKSSEKELH RGFQQLLQEL NQPRDGFQLS LGNALFTDLV VDLQDTFVSA MKTLYLADTF PTNFRDSAGA MKQINDYVAK QTKGKIVDLL KNLDSNAVVI MVNYIFFKAK WETSFNHKGT QEQDFYVTSE TVVRVPMMSR EDQYHYLLDR NLSCRVVGVP YQGNATALFI LPSEGKMQQV ENGLSEKTLR KWLKMFKKRQ LELYLPKFSI EGSYQLEKVL PSLGISNVFT SHADLSGISN HSNIQVSEMV HKAVVEVDES GTRAAAATGT IFTFRSARLN SQRLVFNRPF LMFIVDNNIL FLGKVNRP
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 45.9 kDa (408aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 1mM DTT and 10% glycerol.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Serpin A5, also known as PCI (Protein C Inhibitor) or PAI3 (plasminogen activator inhibitor 3), is a member of the serpin serine proteinase inhibitor family. This protein inhibits plasminogen activators as well as activated protein C. Serpin A5 is secreted in plasma, but is also expressed in liver. Serpin A5 is involved in cell inflammation, proliferation, apoptosis, tumour cell migration, invasion, and metastasis. Recombinant Serpin A5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of Serpin A5 protein (His tag) (80R-1216) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £272.43
Size: 50 ug
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