SNRPB2 protein (His tag) (80R-1801)
Purified recombinant Human SNRPB2 protein
|Synonyms||U2 small nuclear ribonucleoprotein B protein, SNRPB-2, SNRPB-2 protein, U2 snRNP B protein, SNRPB 2, SNRPB2, SNRPB 2 protein|
Coomassie Blue stained SDS-PAGE of SNRPB2 protein (His tag) (80R-1801)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-225 amino acids: MGSSHHHHHH SSGLVPRGSH MDIRPNHTIY INNMNDKIKK EELKRSLYAL FSQFGHVVDI VALKTMKMRG QAFVIFKELG SSTNALRQLQ GFPFYGKPMR IQYAKTDSDI ISKMRGTFAD KEKKKEKKKA KTVEQTATTT NKKPGQGTPN SANTQGNSTP NPQVPDYPPN YILFLNNLPE ETNEMMLSML FNQFPGFKEV RLVPGRHDIA FVEFENDGQA GAARDALQGF KITPSHAMKI TYAKK|
|Grade & Purity||> 90% pure|
|Molecular Weight||27.6 kDa (245aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 40% glycerol and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||SNRPB2, also known as U2 small nuclear ribonucleoprotein B, belongs to the RRM U1 A/B family. This protein associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A. It may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. Recombinant human SNRPB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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