SOX2 protein (His tag) (80R-1281)
Purified recombinant Human SOX2 protein
|Synonyms||ysb., SRY related HMG box 2 protein, Delta EF2a protein, Transcription factor SOX 2 protein, ANOP3 protein, SOX 2 protein, SRY-box 2 protein, MCOPS3 protein, MGC148683 protein, SOX-2 protein, SRY (sex determining region Y)-box 2 ANOP3 protein, RGD1565646 protein, SOX2, SOX-2, SOX 2, SOX 2 protein, Sex determining region Y box 2 protein, MGC2413 protein, SRY related HMG box gene 2 protein, SRY box containing gene 2 protein, lcc protein, SRY (sex determining region Y) box 2 protein, cb236 protein|
Coomassie Blue stained SDS-PAGE of SOX2 protein (His tag) (80R-1281)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-200 amino acids: MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY LEHHHHHH|
|Grade & Purity||> 90% pure|
|Molecular Weight||23.1 kDa (208aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 200mM NaCl, 2mM DTT, and 40% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. This Protein is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Recombinant human SOX2 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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