SPAG8 antibody (70R-2385)
Rabbit polyclonal SPAG8 antibody raised against the N terminal of SPAG8
Overview
Overview
| Synonyms | Polyclonal SPAG8 antibody, Anti-SPAG8 antibody, SPAG-8, SMP1 antibody, hSMP-1 antibody, SPAG 8 antibody, Sperm Associated Antigen 8 antibody, SPAG3 antibody, SPAG 8, BS-84 antibody, SPAG8, MGC26201 antibody, SPAG-8 antibody, HSD-1 antibody |
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| Specificity | SPAG8 antibody was raised against the N terminal of SPAG8 |
| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | SPAG8 antibody was raised using the N terminal of SPAG8 corresponding to a region with amino acids SGPVLGSSSGAGHGSGSGSGPGCGSVPGSGSGPGPGSGPGSGPGHGSGSH |
| Assay Information | SPAG8 Blocking Peptide, catalog no. 33R-8479, is also available for use as a blocking control in assays to test for specificity of this SPAG8 antibody |
Images
Western Blot analysis using SPAG8 antibody (70R-2385)
SPAG8 antibody (70R-2385) used at 1 ug/ml to detect target protein.
SPAG8 antibody
Western Blot analysis using SPAG8 antibody (70R-2385)
SPAG8 antibody (70R-2385) used at 1 ug/ml to detect target protein.
Specifications
| Host | Rabbit |
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| Method of Purification | Affinity purified |
| Molecular Weight | 53 kDa (MW of target protein) |
| Form & Buffer | Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of SPAG8 antibody in PBS |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 1 ug/ml |
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Storage & Safety
| Storage | Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles. |
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General Information
| Biological Significance | The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. SPAG8 is recognised by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. |
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