TACI antibody (70R-TG007)

Affinity purified Goat polyclonal TACI antibody

Synonyms Polyclonal TACI antibody, Anti-TACI antibody, Transmembrane activator and CAML interactor antibody, TNFRSF13B antibody
Specificity Human TAC1
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen TACI antibody was raised in goat using highly pure recombinant human TACI as the immunogen.

Specifications

Host Goat
Molecular Weight 17.8 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TACI, a member of the TNF Receptor superfamily, is expressed in the small intestine, spleen, thymus, peripheral blood leukocytes, activated T cells, and resting B cells. TACI binds to both APRIL and BAFF and can stimulate the activation of transcription factors; NF-kappaB, AP-1, and mediates calcineurin dependent activation of NF-AT (nuclear-factor of activated T cells). TACI also plays a key role in the stimulation of B and T cell function. Soluble TACI inhibits APRILstimulated proliferation of primary B-cells by blocking the binding of APRIL to the membrane anchored TACI receptor.

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Availability: In stock

Price: £180.28
Size: 50 ug
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