TFF1 protein (His tag) (80R-1885)
Purified recombinant TFF1 protein
|Synonyms||TFF-1 protein, TFF 1 protein, TFF1, HP1.A protein, HPS2 protein, BCEI protein, TFF-1, pNR-2 protein, TFF 1, pS2 protein|
Coomassie Blue stained SDS-PAGE of TFF1 protein (His tag) (80R-1885)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||25-84 amino acids: MGSSHHHHHH SSGLVPRGSH MEAQTETCTV APRERQNCGF PGVTPSQCAN KGCCFDDTVR GVPWCFYPNT IDVPPEEECE F|
|Grade & Purity||> 90% pure|
|Molecular Weight||9.0kDa (81aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 20% glycerol, 100mM NaCl and 0.1mM PMSF.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||TFF1 (Trefoil factor 1) is member of trefoil family, characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. TFF1 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. Recombinant human TFF1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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