TIFF1 protein (30R-AT077)

Purified recombinant Human TIFF1 protein

Synonyms BCEI protein, TIFF-1 protein, HP1.A protein, pS2 protein protein, PNR2 protein, TIFF1, TIFF-1, Breast Cancer Estrogen-Inducible protein protein, TIFF 1, TIFF-1 protein, TIFF 1 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of TIFF1 protein corresponding to amino acids EAQTETCTVA PRERQNCGFP GVTPSQCANK GCCFDDTVRG VPWCFYPNTI DVPPEEECEF.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 6.7 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its ability to chemoattract human MCF-7 cells using a concentration 5-10 ug/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF1 is essential for normal differentiation of the antral and pyloric gastric mucosa and functions as a gastric-specific tumor suppressor gene. Recombinant human TFF1 is a 6.7 kDa monomeric protein consisting of a 60 amino acid polypeptide chain, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.

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Availability: In stock

Price: £180.28
Size: 20 ug
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