TIMP1 antibody (70R-TR018)

Affinity purified Rabbit polyclonal TIMP1 antibody

Synonyms Polyclonal TIMP1 antibody, Anti-TIMP1 antibody, TIMP 1 antibody, TIMP 1, TIMP-1 antibody, Tissue inhibitor of metalloantibodyases: Fibroblast collagenase inhibitor; Erythroid-potentiating activity antibody, TIMP1, TIMP-1 antibody, TIMP-1
Specificity Human TIMP1
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen TIMP1 antibody was raised in rabbit using highly pure recombinant human TIMP-1 as the immunogen.

Specifications

Host Rabbit
Molecular Weight 20.6 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-2 ug/ml, Inhibition: 5 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TIMP1 is an extracellular inhibitor of MMPs (see above) including MMP1, 2, 3, 7, 8, 9, 10, 11, 12, 13, and 16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors.

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Availability: In stock

Price: £180.28
Size: 50 ug
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