TNF Receptor Type I antibody (70R-TR013)

Affinity purified Rabbit polyclonal TNF Receptor Type I antibody

Synonyms Polyclonal TNF Receptor Type I antibody, Anti-TNF Receptor Type I antibody, Soluble Tumor Necrosis Factor type I antibody, p55 antibody, TNFR60 antibody, TNFRSF1A antibody, TNFAR antibody, CD120a antibody, TNF-R55 antibody, TNF Receptor I antibody, TNF Receptor 1 antibody
Specificity Human TNF receptor
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen TNF receptor type I antibody was raised in rabbit using highly pure recombinant human sTNF-receptor as the immunogen.

Specifications

Host Rabbit
Molecular Weight 18.3 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-2 ug/ml, Inhibition: 0.9-1.1 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TNFR1 belongs to the TNFR superfamily of transmembrane proteins, and is expressed in most cell types. Binding of either TNF-alpha or TNF-beta to TNFR1 initiates a signal transduction pathway that results in the activation of the transduction factor NF kb, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis. Soluble TNF Receptor I (sTNFR1) is capable of inhibiting TNF-alpha and TNF-beta activities by acting as a decoy receptor that serves as a sink for the TNF ligands.

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Availability: In stock

Price: £180.28
Size: 50 ug
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