TREM2 antibody (10R-1115)

Mouse monoclonal TREM2 antibody

Synonyms Monoclonal TREM2 antibody, Anti-TREM2 antibody, TREM 2 antibody, TREM-2 antibody, triggering receptor expressed on myeloid cells 2a antibody, TREM 2, TREM-2, Trem2b antibody, triggering receptor expressed on myeloid cells 2 isoform 1 antibody, triggering receptor expressed on myeloid cells 2 antibody, Trem2c antibody, TREM2, TREM-2 antibody, Trem2a antibody
Specificity Human
Cross Reactivity Human, Mouse
Applications ELISA, WB
Immunogen TREM2 antibody was raised in mouse using recombinant human TREM2 (19-161aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 2B5
Isotype IgG3 kappa
Source Anti-human TREM2 antibody, clone 2B5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TREM2 protein.
Method of Purification TREM2 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The triggering receptor expressed on myeloid cells-2 (TREM2) is a membrane protein that interacts with the TYROBP protein. The TREM2 and TYROBP proteins form a complex that transmits chemical signals to activate the cell. This complex is involved in the growth and development of several types of immune cells, particularly dendritic cells and activates these cells, triggering an inflammatory response to injury or disease. And the TYROBP-TREM2 complex also activates cells in the skeletal system and in the brain and spinal cord (central nervous system).

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Availability: In stock

Price: £212.33
Size: 100 ul
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