Troponin I antibody (Skeletal Muscle) (10R-T126b)

Mouse monoclonal Troponin I antibody (Skeletal Muscle)

Synonyms Monoclonal Troponin I antibody (Skeletal Muscle), Anti-Troponin I antibody (Skeletal Muscle)
Specificity Human
Cross Reactivity To be determined by end-user
Applications ELISA, WB
Immunogen Troponin I antibody (skeletal Muscle) was raised in mouse using human skTnI as the immunogen.


Host Mouse
Clone 12F10
Isotype IgG2b
Method of Purification Troponin I antibody (Skeletal Muscle) was purified by chromatography on protein A Sepharose.
Form & Buffer IgG purified by protein A sepharose and supplied in PBS, pH 7.4, 0.1 % NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.

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Availability: In stock

Price: £351.72
Size: 1 mg
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