Troponin I protein (Cardiac) (30-AT63)

Purified Recombinant Human Troponin I protein (Cardiac)

Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 24 kDa
Form & Buffer Supplied in 6M Urea, 50mM Tris, pH 8.0
Concentration Batch dependent - please inquire should you have specific requirements

Storage & Safety

Storage Aliquot and store at -25 deg C. Avoid repeated freeze/thaw cycles
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.

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Availability: In stock

Price: £418.65
Size: 100 ug
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