Troponin I Type 1 antibody (70R-3601)

Rabbit polyclonal Troponin I Type 1 antibody

Synonyms Polyclonal Troponin I Type 1 antibody, Anti-Troponin I Type 1 antibody, TNN1 antibody, DKFZp451O223 antibody, TNNI1 antibody
Cross Reactivity Human,Mouse,Rat
Applications IHC, WB
Immunogen Troponin I Type 1 antibody was raised using a synthetic peptide corresponding to a region with amino acids MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIP
Assay Information Troponin I Type 1 Blocking Peptide, catalog no. 33R-6276, is also available for use as a blocking control in assays to test for specificity of this Troponin I Type 1 antibody

Images

Immunohistochemical staining using Troponin I Type 1 antibody (70R-3601)

Troponin I Type 1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 21 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of TNNI1 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.5 ug/ml; IHC: 4-8 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.

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Images

  • Immunohistochemical staining using Troponin I Type 1 antibody (70R-3601) | Troponin I Type 1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X.
  • Western Blot analysis using Troponin I Type 1 antibody (70R-3601) | Troponin I Type 1 antibody (70R-3601) used at 0.5 ug/ml to detect target protein.

Availability: In stock

Price: £272.51
Size: 50 ug
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