Troponin T protein (His tag) (80R-1156)

Purified recombinant Human Troponin T protein

Synonyms MGC3889 protein, Troponin T type 2 (cardiac) protein, TnTC protein, CMPD2 protein, CMH2 protein, cardiac isoform 3 Cardiac muscle troponin T protein, Troponin T cardiac muscle protein, Cardiomyopathy hypertrophic 2 protein, RCM3 protein, Troponin T2 cardiac., Troponin T type 2 cardiac protein, Troponin T type 2 protein, CMD1D protein, TNNT2 protein, TNNT 2 protein, cTnT protein, cardiac isoform 3 protein, Cardiomyopathy dilated 1D (autosomal dominant) protein, Troponin T type 2 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Troponin T protein (His tag) (80R-1156)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-285 amino acids: MGSSHHHHHH SSGLVPRGSH MSDIEEVVEE YEEEEQEEAA VEEQEEAAEE DAEAEAETEE TRAEEDEEEE EAKEAEDGPM EESKPKPRSF MPNLVPPKIP DGERVDFDDI HRKRMEKDLN ELQALIEAHF ENRKKEEEEL VSLKDRIERR RAERAEQQRI RNEREKERQN RLAEERARRE EEENRRKAED EARKKKALSN MMHFGGYIQK TERKSGKRQT EREKKKKILA ERRKVLAIDH LNEDQLREKA KELWQSIYNL EAEKFDLQEK FKQQKYEINV LRNRINDNQK VSKTRGKAKV TGRWK
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 36.4 kDa (305aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Troponin T, also known as TNNT2, is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with restrictive and dilated cardiomyopathy. Recombinant human TNNT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of Troponin T protein (His tag) (80R-1156) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £316.49
Size: 100 ug
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