UBE2D1 antibody (70R-1158)

Rabbit polyclonal UBE2D1 antibody

Synonyms Polyclonal UBE2D1 antibody, Anti-UBE2D1 antibody, UBED1 2 antibody, UBC4/5 antibody, UBED1-2, SFT antibody, E2(17)KB1 antibody, Ubiquitin-Conjugating Enzyme E2D 1 antibody, UBE2D1, UBED1 2, UBCH5 antibody, UBCH5A antibody, Ubc4/5 Homolog Yeast antibody, UBED1-2 antibody
Cross Reactivity Human,Mouse,Rat,Dog
Applications WB
Immunogen UBE2D1 antibody was raised using a synthetic peptide corresponding to a region with amino acids SQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHARE
Assay Information UBE2D1 Blocking Peptide, catalog no. 33R-8734, is also available for use as a blocking control in assays to test for specificity of this UBE2D1 antibody

Images

Western Blot analysis using UBE2D1 antibody (70R-1158)

UBE2D1 antibody (70R-1158) used at 1.25 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Total IgG Protein A purified
Molecular Weight 16 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of UBE2D1 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1.25 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

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Images

  • Western Blot analysis using UBE2D1 antibody (70R-1158) | UBE2D1 antibody (70R-1158) used at 1.25 ug/ml to detect target protein.

Availability: In stock

Price: £220.34
Size: 100 ug
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