VASP antibody (70R-10267)

Affinity purified rabbit polyclonal VASP antibody

Synonyms Polyclonal VASP antibody, Anti-VASP antibody, vasodilator-stimulated phosphoprotein antibody
Cross Reactivity Human
Applications WB
Immunogen VASP antibody was raised in rabbit using the C terminal of VASP as the immunogen
Assay Information VASP Blocking Peptide, catalog no. 33R-8488, is also available for use as a blocking control in assays to test for specificity of this VASP antibody

Images

Western Blot analysis using VASP antibody (70R-10267)

Western Blot showing VASP antibody used at a concentration of 1 ug/ml against Jurkat Cell Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

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Images

  • Western Blot analysis using VASP antibody (70R-10267) | Western Blot showing VASP antibody used at a concentration of 1 ug/ml against Jurkat Cell Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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