VASP antibody (70R-10268)

Affinity purified rabbit polyclonal VASP antibody

Synonyms Polyclonal VASP antibody, Anti-VASP antibody, vasodilator-stimulated phosphoprotein antibody
Cross Reactivity Human
Applications WB
Immunogen VASP antibody was raised in rabbit using the middle region of VASP as the immunogen
Assay Information VASP Blocking Peptide, catalog no. 33R-10020, is also available for use as a blocking control in assays to test for specificity of this VASP antibody

Images

Western Blot analysis using VASP antibody (70R-10268)

Western Blot showing VASP antibody used at a concentration of 1 ug/ml against Fetal Heart Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

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Images

  • Western Blot analysis using VASP antibody (70R-10268) | Western Blot showing VASP antibody used at a concentration of 1 ug/ml against Fetal Heart Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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