VCL antibody (70R-10238)

Affinity purified rabbit polyclonal VCL antibody

Synonyms Polyclonal VCL antibody, Anti-VCL antibody, CMH15 antibody, CMD1W antibody, vinculin antibody, MVCL antibody
Cross Reactivity Human
Applications WB
Immunogen VCL antibody was raised in rabbit using the C terminal of VCL as the immunogen
Assay Information VCL Blocking Peptide, catalog no. 33R-7332, is also available for use as a blocking control in assays to test for specificity of this VCL antibody

Images

Western Blot analysis using VCL antibody (70R-10238)

Western Blot showing VCL antibody used at a concentration of 1 ug/ml against HepG2 Cell Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

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Images

  • Western Blot analysis using VCL antibody (70R-10238) | Western Blot showing VCL antibody used at a concentration of 1 ug/ml against HepG2 Cell Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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