ZAP70 antibody (70R-10263)

Affinity purified rabbit polyclonal ZAP70 antibody

Synonyms Polyclonal ZAP70 antibody, Anti-ZAP70 antibody, FLJ17670 antibody, SRK antibody, TCR associated protein kinase 70kDa antibody, ZAP70, STD antibody, ZAP-70 antibody, ZAP-70, FLJ17679 antibody, ZAP 70, ZAP-70 antibody, ZAP 70 antibody, TZK antibody, zeta-chain
Cross Reactivity Human
Applications WB
Immunogen ZAP70 antibody was raised in rabbit using the N terminal of ZAP70 as the immunogen
Assay Information ZAP70 Blocking Peptide, catalog no. 33R-6365, is also available for use as a blocking control in assays to test for specificity of this ZAP70 antibody

Images

Western Blot analysis using ZAP70 antibody (70R-10263)

Western Blot showing ZAP70 antibody used at a concentration of 1 ug/ml against Fetal Lung Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

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Images

  • Western Blot analysis using ZAP70 antibody (70R-10263) | Western Blot showing ZAP70 antibody used at a concentration of 1 ug/ml against Fetal Lung Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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